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NPI-001 is more lipophilic and more easily permeates cell membranes than NAC

Unique symptoms include electrical shocks, ice pick pains, non specific and central paresthesias (that may be related to autonomics), internal vibration / tremor, increased sensitivity / reactions due to limbic system involvement

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In published animal pharmacology it is administered in tiny amounts nanomole quantities into the brain ventricle, or micromole-per-kilogram amounts subcutaneously in rodents to study opioid analgesia [3] [5]

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