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In animal models, oral BPC-157 reduced gut-ulcer lesions by up to 60% and accelerated tendon healing within two weeks

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The SURMOUNT-5 trial directly compared the two medications and found tirzepatide produced approximately 20 percent weight loss compared to 14 percent for semaglutide

However, the key limitations of existing studies lie in small clinical sample sizes without multicenter validation and unstandardized intervention protocols in animal models, both of which impede clinical translation

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