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Larsen et al

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Dietary supplementation of grape polyphenol, which contained resveratrol, to rats with punctured discs reduced the behavioral sensitivity and gene expression levels of proinflammatory cytokines in DRGs but failed to alleviate disc degeneration or change the proinflammatory cytokine level in IVD

Taking more than 3,000mg daily can cause dangerous glutathione depletion and liver damage

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First isolated in the 1970s by Dr