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adult population (BMI of 30 or higher) peaked around 2017-2020 (and may be declining slowly),[2] rates of severe obesity (BMI or 40 or higher) continue to climb steadily (currently around 10%)

These include modifying nanocarriers to enhance permeability, transporting enzymes that degrade the extracellular matrix, and engineering multifunctional nanocarriers

The most common side effects were of a gastrointestinal nature and were in line with the profile known for GLP-1 drugs

The best outcomes still return to the same foundations: Nutrition, movement, sleep, stress management and long-term behavioural change

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