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Treatment of the CB1 -/- mice with low-dose dexamethasone did not significantly suppress their corticosterone levels and surprisingly caused a paradoxical rise in ACTH levels when compared to the wild-type, although high-dose dexamethasone suppressed corticosterone and ACTH to the same degree in both CB1 -/- and CB1 +/+ mice

10.1002/bdr2.1010 36 JenkinsL

it plays a key role in the liver's detoxification process by binding to toxins and making them water-soluble so they can be excreted

Furthermore, the methodology used to assess body composition may influence outcomes

FDA Disclaimer: Compounded medications discussed in this article are not FDA-approved finished drug products and are not reviewed by the FDA for safety, effectiveness, or quality before marketing

Simeon et al., 2000