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Regular gentle stretching of the calf muscles, particularly before bedtime, may reduce the frequency of nocturnal leg cramps

When the medication is mixed correctly, patients are less likely to experience unwanted side effects, making their weight loss journey safer and more manageable

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2021 Aug 5;385(6):503-515

b Estimated using an ANCOVA based on data irrespectively of discontinuation of trial product or initiation of rescue medication adjusted for baseline value, background medication and region

Weight loss occurs in a dose-dependent way and exhibits a biphasic pattern: an initial quick phase induced by decreased calorie intake, followed by a slower phase indicative of metabolic tolerance and enduring behavioural modifications