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Molecular docking studies demonstrated hydrogen bond formation between polar residues of quercetin and the aldose reductase amino acids Leu-300 and Thr-113, which are critical players in aldose reductase catalysis and inhibition [88]

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What Researchers Are Exploring Sublingual Peptide Bioavailability The sublingual mucosa provides direct access to the systemic circulation via the lingual veins, offering a faster and more direct absorption pathway than gastrointestinal delivery

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Miyazaki Y, Kawano H, Yoshida T, Miyamoto S, Hokamaki J, Nagayoshi Y, Yamabe H, Nakamura H, Yodoi J, Ogawa H: Pancreatic B-cell function is altered by oxidative stress induced by acute hyperglycaemia