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External validity is improved and evaluation across different food patterns and sociodemographic situations is made possible by the inclusion of more than 70 research from various geographic locations

Heart Fail Rev (2008) 13:32137 10.1007/s10741-007-9062-x [DOI] [PubMed] [Google Scholar] 146.Stragier B, Sarre S, Vanderheyden P, Vauquelin G, Fournie-Zaluski MC, Ebinger G, et al

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None of this diminishes the compounds scientific interest

Non-optimised filling parameters can lead to losses and a high reject rate during visual inspection due to a high fill-weight variability or filling needle clogging, which can potentially lead to abortion of the filling process and the need to discard the remaining bulk solution

Miss two or more, and you are taking an avoidable risk with both your research budget and your results