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For instance, a large network meta-analysis showed that SGLT-2 inhibitors reduced hospitalization for HF and renal composite outcome more than GLP-1RA [15], and that in patients with cardiovascular disease, SGLT-2 inhibitors show significant reduction in both heart failure (HF) hospitalizations and mortality for patients with HF and reduced ejection fraction [16]

Including these markers provides a more comprehensive view of why you might still feel tired or sluggish even if your TSH is "normal."

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In particular, data in pharmacovigilance monitoring databases like FAERS rely on voluntary reporting which can be heavily influenced by media attention drawn to potential relationships

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The window for proactive action is narrowing