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However, because they slow gut motility, they may increase susceptibility in some individualsparticularly those with existing risk factors such as IBS, constipation, or prior gastrointestinal infections
Ekta Kapoor, associate Professor of Medicine at Mayo Clinic, writes women with a greater self-reported menopause symptom burden had higher cortisol levels, signifying greater physiological stress. This keeps women alert at night, contributing to longer stretches of wakefulness, non-restorative rest, a buildup of sleep debt and the lower quality of life that comes with extreme fatigue, in general
Metabolic Optimization Even at sub-therapeutic doses, GLP-1 receptor agonists improve insulin sensitivity, reduce post-meal glucose excursions, decrease appetite, and support favorable shifts in body composition
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