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Despite lower efficacy and tolerability shown by nasally administered PYY agonists in early studies, long-acting subcutaneous PYY receptor agonists such as PYY 1875 are undergoing early-phase clinical trials to evaluate their safety and effectiveness as monotherapy or in combination with GLP-1 receptor agonists for the treatment of obesity

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Cancer Chemother Pharmacol (2016) 77(6):110324

Taylor, D

The cutoff criteria were p _value 0.586, and filtered out RNAs with low expression values (the number of samples with normalized gene expression 0.02 for the brown module (TCGA) and the black module (GSE15471) respectively