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Oxidative stress analysis confirmed that PCC samples had significantly higher levels of DNA damage (8-OHdG) than the convalescent group, whereas antioxidant markers, such as reduced and oxidized glutathione (GSH and GSSG), were significantly lower in PCC samples than in uninfected controls
The natural production of glutathione tends to diminish with age, primarily due to a decrease in the body's ability to synthesise it
300 The excised target DNA, up to 100 kb, can then be ligated through methods such as Gibson assembly into expression vectors
Activation of these receptors regulates lipid and glucose metabolism, promotes bile acid synthesis and transport, and influences energy metabolism and anti-inflammatory responses, thereby contributing liver health and metabolic homeostasis