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The duration of follow-up varied across the studies, spanning from 12 to 48 months, with an average follow-up duration of 27.5 months

In summary, this real-world comparative effectiveness study found that adults without diabetes initiating tirzepatide for obesity management achieved greater weight reduction and improvements in select cardiometabolic risk parameters at 6 months than those initiating semaglutide

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And the muscle masses the way to handle that problem is to be physically active

Here is the complete tirzepatide escalation schedule

If you want another patient-friendly explanation of how reflux can show up on these medications, our guide on GLP-1 medications and acid reflux is worth reading