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These signals can shift gut movement, pain sensing, and barrier strength

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The most common experience during week 1 includes: Mild-to-moderate nausea, especially after eating Reduced appetite and an earlier feeling of fullness Possible fatigue or low energy as calorie intake drops Mild headache, often linked to reduced food and fluid intake The starting dose for Ozempic is 0.25 mg weekly

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Bloody diarrhea, black tarry stools, severe abdominal cramping, or vomiting warrant medical evaluation