These include: Pre-existing constipation or slow transit constipation Inadequate dietary fibre intake Insufficient fluid consumption Reduced physical activity levels Concurrent medications with constipating effects (such as opioids, certain antidepressants, or iron supplements) Older age , where baseline colonic motility may already be reduced The severity of constipation often correlates with the dose of medication and may be more pronounced during dose escalation phases
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The findings revealed markedly accelerated subcutaneous tumor growth in obese females lacking ovarian hormones
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Medical studies back these reports, revealing that the drugs mechanism, which involves altering digestive processes, may contribute to these complications
Yet, bridging the gap from lab to market was not straightforward
