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I have this conversation with patients openly, and in my experience, once they understand the reasoning, most are comfortable with it

Treatment focuses on the cause of impaired production, copper loading or protein loss

doi: 10.1016/j.molmed.2022.07.002 65 ChenALiJShenNHuangHHangQ

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However, a pooled analysis of the two trials that employed ALCAR found no significant effect of ALCAR and L-carnitine on sperm concentration, motility, and morphology (114)