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Prolonged or repeated exposure to MDMA can lead to long-term abnormalities in the serotonergic system, including decreased levels of serotonin (5-HT) and its major metabolites in the thalamus, striatum, and cortex

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Although residues C32 and C88 of PfGrx are redox-inactive during the monothiol mechanism, they both facilitate the deglutathionylation of GSSR substrates

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