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Between 15-40% of people over 60 have low serum B12 levels (Pacholok & Stuart, 2011)

As a general clinical principle: Retest HbA1c no sooner than three months after commencing B12 replacement therapy, and ideally once haematological recovery has been confirmed Confirm haematological recovery normalisation of MCV and haemoglobin before interpreting the repeat HbA1c as reliable Use interim glucose monitoring such as fasting plasma glucose, OGTT, or self-monitored blood glucose (SMBG) to assess glycaemic control during the treatment period

Bacteriostatic Water (BAC) is sterile water that contains 0.9% benzyl alcohol, which acts as a preservative

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One reason is being low in a type of compound produced within the stomach called intrinsic factor (a type of glycoprotein), which combines with vitamin B12 once consumed in order to allow it to be absorbed

Prediatr., 551-556, 1981