first large study of glp 1 receptor agonists during pregnancy GLP-1 Agonist Use in The hidden impact of GLP‐1

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Concurrently, damage-associated molecular patterns (DAMPs), such as HMGB1 and mitochondrial DNA, are released from necrotic or apoptotic cells, activating toll-like receptors (TLR4) and NOD-like receptors, thereby promoting inflammation through recruitment of neutrophils and monocytes into the myocardium

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J Clin Neurosci 19(10):14501453