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Though this ancient gene family has been exhaustively studied in different organisms, still the information available about its sequences and gene organization understates its functional diversity

We propose a cellular model of CVS in which an aberrant ion gradient begets mitochondrial dysfunction which begets further anomalous ion gradients, etc., forming a pathogenic vicious cycle leading to cellular hyperexcitability (Figure 1)

PMDD (Premenstrual Dysphoric Disorder) includes severe symptoms like extreme mood swings, irritability, depression, anxiety, fatigue, and intense cravings for foods

The Medicines and Healthcare products Regulatory Agency (MHRA) has updated the product information to include the small risk of severe acute pancreatitis in patients taking GLP-1s, prescribed for treating type 2 diabetes and weight management

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A limitation of our study is that dosages were not systematically captured