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doi: 10.1113/jphysiol.2002.033811 55 ZhangJJinHZhangWDingCOKeeffeSYeMet al

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Switching may be considered for several reasons, including: Inadequate weight loss results Side effect intolerance Changes in insurance coverage Plateauing on current medication Seeking stronger appetite suppression or satiety Most transitions involve cross-titration, gradually adjusting doses to minimize gastrointestinal side effects and support a smooth switch

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