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However, at a constant concentration of GSH with varying concentrations of GSH, Lineweaver-Burk and Hofstee plots of initial velocity as function of glutathione concentration revealed apparent K m and Vm values: 27.62 M and 0.66 nmoles ml -1 min -1 respectively

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This change means compounding pharmacies will face stricter guidelines, potentially limiting patient access to these therapies unless they are prescribed under specific, FDA-approved conditions or clinical trials