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If you become pregnant or plan to become pregnant, discontinue semaglutide at least 2 months before conception

If a patient regains more than 5% of body weight before reaching the zero-dose step, that signals the need to pause the taper, reassess behavioral supports, and consider whether full discontinuation is the right goal

Swirl gently until the powder dissolves completely

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Elevated blood sugar and insulin blunt GH release, reducing peptide effectiveness