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6.4.2 Laboratory and neurophysiological examinations Decreased Vit B12 levels and elevated Hcy and MMA are hallmark findings in NO-induced neuropathy (Warendorf et al., 2022)

A drug can be metabolized in the gut wall (eg, by the CYP3A4 enzyme system) or even in the portal blood, but most commonly it is the liver that is responsible for metabolism before the drug reaches the systemic circulation

These strategies will be crafted to address specific barriers identified through our research, and their implementation will be closely monitored and adjusted based on ongoing evaluations

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