glp 1 resting heart rate Does GLP-1 Raise Rate? Safety and Evidence GLP-1 receptor agonists and myocardial

JAMA 282, 15231529

S6 show that both GLP-1RA and SGLT-2 inhibitors were associated with a lower risk (13% and 14%, respectively) as compared with placebo and DPP-4 inhibitors (11% and 12%, respectively), although the difference in risks was significant for SGLT-2 vs DPP-4 inhibitors only

benefit was preserved in the prespecified subgroup receiving sodium-glucose cotransporter-2 inhibitors (SGLT2i) at baseline, which supports combined GLP-1RA + SGLT2i use as a supported option pursuing complementary pathways [4], [33]

People with poorly controlled type 2 diabetes often experience fatigue due to fluctuating blood glucose levels

However, most people on GLP-1s experience reduced intake at some point, making supplementation a helpful safety netespecially during dose increases or periods of low appetite

GLP-1 meds can also cause a general reduced desire to drink