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Their pleiotropic effects, which range from anti-inflammatory, antioxidant, and metabolic regulation to neuroprotective and endothelial-stabilizing properties, are mediated through complex intracellular pathways, including the PI3K/Akt, AMPK, and NF-B signaling pathways

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Carnitine is key as the fewer fatty acids that get into a cell, the less energy that can be burned

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The morphology of FLS was assessed by an inverted microscope with a Leica Qwin System (Leica, Germany)

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Temporal changes in baseline characteristics between the later and earlier time periods were evaluated separately for the SGLT2i and GLP-1 RA cohorts using the standardized mean difference (SMD) in the level of each covariate, with SMDs of 0.2, 0.5, and 0.8 considered to correspond to small, medium, and large differences, respectively [20]

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A systematic review of the evidence in humans and non-human primates Human Reproduct Open 2024 045 R Evstatiev C Gasche 2012 Iron sensing and signalling Gut 61 6 933 52 R Kapoor VK Sirohi K Gupta A Dwivedi 2019 Naringenin ameliorates progression of endometriosis by modulating Nrf2/Keap1/HO1 axis and inducing apoptosis in rats J Nutrit Biochem 70 215 26 Rossi H-R

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