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7 In rats treated with cysteamine (which depletes somatostatin and dysregulates GH release), BPC-157 administration normalized GH receptor expression in peripheral tissue and attenuated the duodenal lesions characteristic of cysteamine-induced damage

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In summary, the new method of cycloalka[ b ]indole library construction reported here has identified JWU-A021 to be a GLP-1 secretagogue with potent TRPA1 activating properties, not only in STC-1 cells, but also in mouse L-cells