Enterohepatic Takeda G-protein coupled receptor 5 agonism in metabolic dysfunction-associated fatty liver disease and related glucose dysmetabolism
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They may cause less bloating than some other fibres and may be better tolerated during the adjustment period to GLP-1 therapy, though individual responses vary
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Their effects on the individual components of MACE, myocardial infarction (reduced in LEADER and Harmony Outcomes), and stroke (reduced in SUSTAIN-6 and REWIND), varied in each trial (Table 1)
13 References Xultophy Summary of Product Characteristics, September 2014