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In humans, GH's bone-building effects require months of sustained IGF-1 elevation this is a long-game benefit

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Endocr Regul 52(2):5968 El-Sayed SN, Hussein AA, Elshamy AI, Farrag AR, Ahmed RA (2022) Ameliorative impacts of Dactyloctenium aegyptium and Parapholis incurva ethanolic extracts on sodium fluoride induced pathological alterations in the thyroid gland in male rats

Although the progression of disease and the organ damage they cause is quite different, chronic fatigue is a lingering condition they all share