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125 GCGR knockout mice produced in one study had islet alpha-cell hyperplasia and these mice were additionally shown to have large increases of glucagon and GLP-1 levels in circulation, but interestingly they had lower plasma glucose levels throughout the day, similar insulin levels and improved glucose tolerance compared to GCGR+ control animals

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A general method to fine-tune fluorophores for live-cell and in vivo imaging

"Mini-Meal" Snacks for When You Need More: On days when I'm too swamped for a proper meal, some of these "snacks" become more like a quick, balanced mini-meal

& Topol, E