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While not a side effect per se, I also warn my patients that methylene blue can stain

You may be at risk of having vitamin B deficiencies if you have Crohn's disease, autoimmune diseases, HIV, are elderly, or have a family history of the disease

There aren't that many other substances people are injecting into themselves where you see that the clinical evidence is so lacking. In recent years, the FDA has warned Americans about the risks of injecting peptides like BPC-157 and TB-500

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[DOI] [PubMed] [Google Scholar] 155.Lushchak VI

Other potential mechanisms underlying the action of NAC on neuropathic pain include the activation of type-9 matrix metalloprotease and the decreased phosphorylation of p38 MAP kinase in the spinal cord [167, 168]