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Good candidates generally have stable health status, understand the experimental nature of the therapy, and commit to appropriate monitoring protocols

Diet high in processed foods, low in antioxidants

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These obese mice also showed activation of microglia and astrocytes and significant immunoreactivity of neuroinflammatory and apoptosis markers, such as TNF-, COX-2, and Caspase-3, in addition to lower expression of neurogenesis and synaptic plasticity markers, such as NeuN, KI-67, CREB-p, and BDNF