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References Richie JP Jr, Leutzinger Y, Parthasarathy S, Malloy V, Orentreich N, Zimmerman JA

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Lycorine, an Amaryllidaceae alkaloid with low toxicity, reduces GPX4 and elevates ACSL4 in renal cancer cells

If we target this mechanism, this preliminary evidence suggests it may help migraine sufferers. The drug was generally well-tolerated, with about 38% of participants reporting mild side effects like nausea and constipation, but none stopped treatment because of them