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How difficult is swallowing dry foods

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While some people feel less hungry after their first dose, it may take a month or more for others to notice this effect

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However, anecdotal reports of shedding are increasing in online forums and patient communities

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Tirzepatide activates both GIP and GLP-1, the two main incretin pathways that regulate appetite, insulin response, and gastric emptying

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1 Steady-state concentrations are reached after roughly five weeks of once-weekly dosing, with substantial carryover from one week to the next

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