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381,382,383,384 They are easily synthesized, possess relatively stable chemical properties, and exhibit a high selectivity

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Ethics declarations ETHICS APPROVAL AND CONSENT TO PARTICIPATE All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards

Weight loss may plateau over time due to counterregulatory hormonal mechanisms that resist further reductions