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Lean Mass Preservation and Pubertal Development It represent critical yet underexplored considerations in the pharmacological management of adolescent obesity

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Rather, it appears to reduce the overall motivational drive toward high-reward behaviors

Drugs that target the known pathophysiological processes and help to counteract or reverse them should be considered

Slowed Metabolism: Muscle burns more calories than fat, so a decrease in muscle mass results in a lower resting metabolic rate, making weight management more challenging

This isn't exhaustive, but it highlights the flexibility required when designing your protocols