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Pelage Pharmaceuticals has emerged as the most visible name in this emerging field
Although past meta-analyses reported substantial reductions in MACE with DPP-4 inhibitors [23], their conclusions were based on studies with small sample sizes and limited numbers of cardiovascular events, which have not been confirmed by the four CVOTs specifically designed to assess the CV safety of DPP-4 inhibitors
Moser said more research is needed that utilizes objective taste and smell testing in addition to patient-reported outcomes, as well as assesses taste both before and after initiation of obesity treatment
Some studies suggest a beneficial effect, while others report exacerbations [65] (see Table 3)
Employees of companies that provide coverage for Medicare Advantage programs will have access to GLP-1 drugs for obesity, but their physicians will have to navigate a prior authorization program