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Crystallographic coordinates of the ternary complex of Pt GSTF8 have been deposited in the PDB as 8AGQ

To identify new regulators of GSC proliferation, we used ethyl methane sulphonate (EMS) to randomly mutagenize a mutant strain carrying a conditional glp-1 gain-of-function ( gf ) allele, which causes the formation of proximal undifferentiated benign germline tumours under restrictive conditions 19,20,21