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What happens to my weight after stopping GLP-1 treatment

(heparin), 10 g/kg i.g

In an animal model, liraglutide reduced the adipokine levels, and alleviated the histopathology of liver of rats in the steatosis [37]

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This regulatory effect is partly mediated via the AMPK/sirtuin-1 (SIRT1) axis, as knockdown of SIRT1 abrogated the lipid-lowering and autophagy-inducing effects of GLP-1RAs, highlighting a crucial role of this pathway in regulating lipid metabolism by facilitating degradation of lipid droplets, thus preventing excessive lipid accumulation (12)