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This is where retatrutide pulls ahead in a way that tirzepatide simply cannot match at any dose, and the data is striking enough to change how researchers think about these compounds

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This creates a vicious, self-perpetuating cycle: neuro-inflammation halts gut motility, halted motility breeds bacterial overgrowth and systemic toxicity, and that toxicity further inflames the nervous system

With honest discussion, patients can choose a plan that protects health today and supports sustainable progress toward a healthier life