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Approximately 50% of HMBi is shielded from ruminal degradation, with the remaining 50% undergoing hydrolysis by rumen microorganisms to HMB and isopropanol (Graulet et al., 2005)

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Another study found that folate levels were positively correlated with Gesell DQ scores in children with ASD, but vitamin B12 levels were not significantly correlated with neurodevelopment in children with ASD (Guo et al., 2021b)

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