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Valproic acid alters fatty acid metabolism, which can lead to serious toxicity including metabolic acidosis, increased ammonia in the blood, liver damage, pancreatitis, bone marrow depression (low platelets, red cells and/or neutrophils) and cerebral edema (brain swelling)

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Omega 3 fatty acids, vitamin C, vitamin D, and sulforaphane have also been studied in ASD, targeting oxidative stress via different mechanisms of action with varying results (25, 3135)

Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin

Supplementation with gamma-glutamylcysteine has shown to increase cellular glutathione levels above homeostasis [14] and therefore proves to have potential value as a preventative therapy for osteoporosis by reducing oxidative stress and optimizing Vitamin D and calcium absorption

Cytochrome P450 oxidoreductase contributes tophospholipid peroxidation in ferroptosis