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The goal is suberythemal exposure enough UV to trigger melanogenesis without causing inflammatory sunburn that inhibits melanin synthesis

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LCS3 induces synergistic inhibition of the glutathione and thioredoxin pathways After demonstrating that LCS3 inhibits the disulfide reductases GSR and TXNRD1, we aimed to establish whether loss of these enzymatic activities is toxic to LUAD but not non-cancerous lung epithelial cells

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Tumor masses were removed after 3 weeks and weighted

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