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Similarly, a 2019 meta-analysis published in Obesity Reviews concluded that weight cycling increases the risk of cardiometabolic disease, systemic inflammation, insulin resistance, and psychological distressespecially among women (Eun-Jung Rhee, 2017)

Nat Commun 15:8408

GLP-1-induced weight loss directly translates to reduced joint stress, slowing cartilage degradation and improving mobility

Acta Biomater 8(1):341349 Li H, Chang J (2013) Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect

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