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Combination with Metformin or Metformin with SGLT-2 Inhibitors In a 26-week, double-blind, double-dummy trial (Trial 4, NCT02863419), 711 adult patients with type 2 diabetes mellitus on metformin alone or metformin with SGLT-2 inhibitors were randomized to semaglutide tablets 14 mg orally once daily, liraglutide 1.8 mg subcutaneous injection once daily or placebo

Fatty Liver Disease Fatty liver disease, often linked to obesity and type II diabetes, may be reversed or prevented with the effective treatment of semaglutide, safeguarding liver function and overall health

Taken together, the available evidence suggests that dual incretin agonism may indeed signal the beginning of a new era in the treatment of metabolic disease

Fine-needle aspiration for fluid was negative