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15% loss is associated with T2DM remission and mortality reduction

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Tirzepatide combines the incretin effects of GLP-1 with GIP, the latter of which contributes to appetite regulation and further reductions in food intake

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However, like any medical treatment, they can come with side effects, including nausea, vomiting, diarrhea, and constipation

If you have a history of heart disease, stroke, or multiple cardiovascular risk factors, phentermine is not just suboptimal, it is contraindicated