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Additionally, severe renal impairment, active pancreatitis, or diabetic retinopathy complications require careful provider evaluation
Acknowledgements This work was supported by the Medical Research Council [grant numbers MR/J01186X/1, G0901321, MR/M006301/1], (the third grant is a UK New Investigator Research Grant supporting MJB)
Interestingly, inhibiting WNT1-expressing spinal afferents increases food intake [37], suggesting a physiological role for this sensory cell type in suppressing food intake
Given the widespread use of GLP-1 medications for weight management and diabetes, the findings could have significant public health implications
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