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PMID: 40384845 J Stroke Cerebrovasc Dis Ropivacaine attenuates cerebral ischemia-reperfusion injury in young male mice by reducing endothelial oxidative stress through activation of the Htr7/cAMP-PKA signaling

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Bottom line Retatrutide is still in clinical trials, with early data suggesting significant weight loss potential, while tirzepatide has FDA approval and proven efficacy and safety history