September 12, 2007
E2F6, E2F7, and E2F8 are members of the E2F family of TF, which play important roles in cell cycle regulation, cell proliferation and survival, and gene expression 57
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However, human, but not rodent, cytotoxic granules contain the antimicrobial peptide granulysin (GNLY), which selectively destroys cholesterol-poor microbial membranes 11,12,13,14 , and GNLY, PFN and Gzms rapidly kill intracellular bacteria 15
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However, its direct impact on human muscle growth remains unproven, requiring further research to understand its full effects