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Additionally, long-term use of metformin is associated with vitamin B12 deficiency 2

No results have been posted to the registry , so the answer for oral drugs taken alongside retatrutide is not yet public

Yes, there can be differences in the dosing schedules (sometimes called titration) and injection volumes between the two medications

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Because the hospitalization outcome included only two studies and showed high heterogeneity, these findings should be interpreted cautiously